Asked for Female | 55 Years
Should I Start Chemotherapy or Oncotype DX Test?
Patient's Query
Hello, my sister discovered she had a breast cancer in March 24, she had a successful lumpectomy in March 28, the pathology report said that tumor was 22 x 23 x 18 mm, has 5 involved lymph nodes, ER strong positive ( score 8 ), PR negative, HER2 negative... after that she did a pet/CT scan in May and the opinion of the radiologist written in the report was " patient with right breast cancer after surgery showing no evidence of hypermetabolic lesion distinctive for loco-regional resudal/recurrence of metastatic disease. I also attached the detailed results of the pet/ct itself. Now does it recommend for her to start chemotherapy or to do oncotype dx test first and btw she had 25 sessions of radiotherapy, so after the surgery ( in March) we had the radiotherapy in ( June) and now we don't know we have to start chemotherapy or do this test first since she has ER positive, HER2 negative and she's postmenopausal. She is 55 yrs old. Now I now your opinion, your advice and recommendations for us. And if she did the test and the result is law and chemotherapy is still recommended for her can she take at least a less intensive chemotherapy regimen.
Answered by Dr. Ganesh Nagarajan
From the information that you were able to share, it sounds like your sister had the necessary treatment done successfully for her breast cancer. Given that she is ERpositive and HER2 negative, the Oncotype DX test can be used to determine whether she requires chemotherapy. If the test indicates low risk, she might not have to undergo intensive chemotherapy. This check is based on the study of the genes present in cancer cells and helps to determine treatment methods. It is important to talk about these options with her oncologist so that the best solution can be found for her case.

Oncologist
Questions & Answers on "Breast Cancer" (70)
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